AZ causes Guillain-Barre syndrome (General)

by dulan drift ⌂, Thursday, July 01, 2021, 13:27 (1242 days ago) @ dan

Here's a whole new serious side effect.

Health Europa: Clinicians in India and England have reported cases of a rare neurological disorder called Guillain-Barre syndrome after individuals were vaccinated against COVID-19.

Seven cases were reported from a regional medical centre in Kerala, India, where around 1.2 million people were vaccinated with the AstraZeneca COVID-19 vaccine. A further four cases were reported from Nottingham, England, in an area in which approximately 700,000 people received the same vaccine.

Annals of Neurology: All seven patients developed severe GBS. The frequency of GBS was 1.4 to 10-fold higher than that expected in this period for a population of this magnitude. In addition, the frequency of bilateral facial weakness, which typically occurs in less than 20% of GBS cases, suggests a pattern associated with the vaccination.

While the benefits of vaccination substantially outweigh the risk of this relatively rare outcome (5.8 per million), clinicians should be alert to this possible adverse event, as six out of seven patients progressed to areflexic quadriplegia and required mechanical ventilatory support.

Why are reports of this only surfacing now? That's one in 172 000 jabs - so given the scale of the vaccination rollout that must already add up to a decent number.

A lot of doctors are big pro-vaxxers - can we rely on them to accurately report side effects? Or will tend to under-report because they don't want to add to vaccine hesitancy?


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