Nature Article: The emergence of the E484K substitution in a B.1.1.7 background represents a threat to the efficacy of the BNT162b2 vaccine. (Pfizer)

Our data suggest that vaccine escape by the virus of current spike-directed vaccines designed against the Wuhan-1 strain will be inevitable, particularly given that E484K is emerging independently and recurrently on a B.1.1.7 (501Y.V1) background, and given the rapid global spread of B.1.1.7.

(B.1.1.7. is the name for the UK variant)

A recent study18 has also shown that variants carrying the E484K substitution resulted in a 3–6-fold reduction in neutralization by sera from individuals who received the mRNA-1273 vaccine.

Finally a study has laid it out in black and white: the Pfizer vaccine (and presumably all of them) don't work against variants.

This confirms what we deduced from the equivocal language that was coming our of Pfizer and their messaging about the possible need for a 'booster'.

Given that variants now are the main form of Covid, the above has serious consequences that appear to be currently being ignored:

Primarily: There is no point injecting everyone with experimental vaccines that don't work. No amount of name-calling against people who point that out is going to change that fact.

Secondly: It's an enormous waste of public money.

The above paper cheerily goes onto say: The (lack of vaccine efficacy) should be mitigated by designing next-generation vaccines with mutated spike sequences and using alternative viral antigens.

But that's illogical. If the virus was able to mutate within months to escape current vaccines then it will do the same to new vaccines. It's chasing your tail.

Luckily for drug companies and scientists, pointlessly chasing your tail at the public's expense results in a financial windfall for the tail chasers.