Alexander Fleming, 1945: (T)he public will demand the drug and … then will begin an era … of abuses. The microbes are educated to resist penicillin and a host of penicillin-fast organisms is bred out which can be passed to another individual and perhaps from there to others until they reach someone who gets a septicemia or a pneumonia which penicillin cannot save.

In such a case, the thoughtless person playing with penicillin treatment is morally responsible for the death of the man who finally succumbs to an infection with penicillin-resistant organisms. I hope this evil can be averted.

Sorry Alexander, that evil couldn't be averted. Well it could have been - but it wasn't.

Worse news - no one was held morally responsible for the boom in hospital acquired infections that persists to today