So there must be some signatures if it is indeed manipulated virus, some slight footprints.

Apparently there is. In August 2020, a collective of scientists on ResearchGate questioned the natural evolution theory, saying "Although based on phylogenetic analysis SARS-CoV-2 seems to be related to BatCoVs RaTG13 or RmYN02 ...(t)he host tropism pattern has major discrepancies compared to other CoVs, raising questions concerning the proximal origin of SARS-CoV-2. "

These guys don't have the mass-media mega-phone that our Proximal Origins guys had but it's a growing tide.