Here's the nightmare scenario - the bio-engineering crossed a bridge that the coronavirus (normally harmless) could never have achieved in nature. This acts like a paradigm shift for coronaviruses and aided by partially effective vaccines, it gradually becomes more and more deadly.

It finally wipes out humanity.

Better write that movie before there's no-one left to watch it.

That's a brilliant premise for a movie! A nightmare scenario for reality, but it would make a great movie. And of course, some antagonist would come up with an evil solution to solve the problem they created, a solution such as putting all the rich, powerful, and as yet uninfected in 5-star bunkers and nuking the rest of the world. This would kill the virus and solve global warming!